Vasculitis
Conditions
Keywords
Vasculitis
Brief summary
The FAMILYVASC study is a prospective observational study which will aim to identify susceptibility loci and genes for systemic vasculitis risk in patients with familial or pediatric forms of vasculitis. Genetic analysis based on whole exome sequencing will be carried out through salivary DNA.
Interventions
GENETICgenetic analysis
Saliva sample collection for genetic analysis
Sponsors
Benjamin Terrier
Study design
Observational model
FAMILY_BASED
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
for subjects with vasculitis * Children and adults * Patients with vasculitis, as defined in the Chapel Hill International Classification in its revised version of 2012 * Patient information and signed informed consent * Pregnant and breastfeeding women can be included in the study Inclusion criteria for healthy subjects * Children and adults * Do not have vasculitis, as defined in the Chapel Hill International Classification in its revised version of 2012, or relatives on the 1st; 2nd; 3rd or 4th degree of a patient with vasculitis * Patient information and signed informed consent * Pregnant and breastfeeding women can be included in the study
Exclusion criteria
* Refusal of consent or inability to obtain consent * Dementia or unauthorized patient, for psychiatric or intellectual failure reasons, to receive information about the protocol and to give informed consent. * Uncooperative patient, or any pathology that could make the patient potentially non-compliant to the study procedures, and patients interned for regulatory or legal reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of susceptibility loci and genes | At the moment of enrollment |
Countries
France
Contacts
Primary ContactBenjamin Terrier, MD, PhD
Backup ContactHicham Kardaoui, MSc
Outcome results
None listed