Pre-Eclampsia
Conditions
Brief summary
Severe preeclampsia is associated with an elevation in intracranial pressure (ICP). Optic nerve sheath diameter is a non-invasive surrogate of invasive ICP measurement. This study targets to evaluate the ICP in patients with or without preeclampsia.
Detailed description
MRI studies have shown that brain edema due to an elevation in ICP develops in up to 70% of women with preeclampsia. Optic nerve sheath diameter is used to estimate the ICP and has been shown to correlate well with invasive ICP measurement. The present study aims to compare ICP using optic nerve sheath diameter in women with or without preeclampsia.
Interventions
DIAGNOSTIC_TESTOptic nerve sheath diameter measurement
Optic nerve sheath diameter measurement is performed with a linear ultrasound probe placed over the eyelid.
Sponsors
Kanuni Sultan Suleyman Training and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 49 Years
Healthy volunteers
No
Inclusion criteria
* Must be diagnosed as preeclampsia * Age must be \> 18 years
Exclusion criteria
* History of previous intracranial pathology or surgery * Glaucoma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ICP | At 6th hour of admission | The difference in ICP estimated with optic nerve sheath diameter measurement among women with or without preeclampsia |
Countries
Turkey (Türkiye)
Outcome results
None listed