Postoperative Pain
Conditions
Brief summary
ESP block advantages include its simplicity, easy identifiable ultrasonographic landmarks and low risk for serious complications as injection is into tissue plane that is distant from pleura, major blood vessels and discrete nerves. Coupled with the fact that the erector spinae muscle and ESP extend down to the lumbar spine, ESP block was hypothesized to be performed at the level of L4. In a recent case report, ultrasound guided ESP block was successfully performed at L4 transverse process level for postoperative analgesia after total hip arthroplasty. However, confirmation of the efficacy of ESP block in hip replacement surgeries needed more investigation.
Detailed description
This study will be performed in Cairo university hospital. Thirty adult patients of both sexes scheduled for hip replacement surgery under spinal anesthesia will be enrolled in the study. All patients meeting the inclusion criteria will be randomly assigned to one of 2 groups, 15 per group: Group E, ESP group (n=15): prior to surgical incision, patients will have ultrasound guided ESP block before spinal anesthesia. Group C, Control group (n=15): prior to surgical incision, patients will have spinal Anesthesia without ESP block . Patients will be randomly allocated by a computer-generated table into one of the study groups, the randomization sequence will be concealed in sealed opaque envelopes.
Interventions
The patients will be in lateral position. A curvilinear array ultrasound probe will be placed in a transverse orientation at L4 level to identify the tip of the L4 transverse process. Local anesthetic infiltration of the superficial tissues, an echogenic 22-G block needle will be inserted inplane to the ultrasound beam in a cranial-to-caudal direction until contact made with the L4 transverse process. Correct location of the needle tip in the fascial plane deep to erector spinae muscle will be confirmed by injecting 0.5-1ml saline and seeing the fluid lifting the erector spinae muscle off the transverse process while not distending the muscle. A total volume of 20ml bupivicaine 0.25% and 20 ml xylocaine 1% will be injected into the ESP on the affected side.
PROCEDUREsubarachonoid block
Local anesthesia 2ml of lidocaine 2% will be applied intradermally to the needle entrance point. A 22-G block needle will be inserted, free cerebrospinal fluid flow will be observed and 20mg of hyperbaric bupivacaine 0.5% and 10μg of fentanyl will be injected for 30 seconds.
Sponsors
Bassant M. Abdelhamid
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged from 40 to 65 years old * Both sexes. * ASA I-II. * Undergo hip replacement surgery. * Body mass index (BMI) from 18 to 35 kg/m2.
Exclusion criteria
* Patient refusal. * Contraindication to regional anesthesia (bleeding disorder, use of any anticoagulants, local infection, etc. ) * BMI \> 35. * Known allergy to local anesthetics. * ASA III-IV. * Patients with difficulty in evaluating their level of pain.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total morphine consumption | 24 hours postoperative | Total morphine consumption in rescue boluses during 1st 24 hrs postoperatively. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue scale | 30 minutes,2,4, 6, 12, and 24 hours postoperative. | Visual analogue scale at the following intervals:30 minutes,2,4, 6, 12, and 24 hours postoperative. |
| Duration of analgesia | 24 hours postoperative | defined as the time interval from completion of local anesthetic administration till first need of rescue analgesic in the form of iv morphine |
| Incidence of complications | 24 hours | Nerve injury, Hematoma formation, LA toxicity, Intravascular injection. |
Countries
Egypt
Outcome results
None listed