Fluid Responsiveness, Modified Prone Position
Conditions
Keywords
Pleth variability index
Brief summary
To investigate whether PVI predicts the fluid responsiveness in modified prone position undergoing posterior approach cervical operation. Furthermore, modified prone position could influence on dynamic variables including stroke volume variation(SVV), pulse pressure variation(PPV) and PVI.
Detailed description
Objective : To compare measurements of pleth variability index (PVI), pulse pressure variation (PPV) and stroke volume variation (SVV) to predict fluid responsiveness in modified prone position or knee-chest position (concord position) for cervical operation. To identify Influence of the modified prone position (concord position) on these variables. Method 1. To assess influence of the position change on PVI and other variables(PPV, SVV) 2. To assess PVI to predict fluid responsiveness at modified prone position
Interventions
OTHERvolume expansion
To assess fluid responsiveness
Sponsors
Asan Medical Center
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to 79 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anaesthesiologists'(ASA) physical status 1-3 * patients who received cervical operation in modified prone position or knee-chest position
Exclusion criteria
* Valvular heart disease * Congestive heart failure, reduced left ventricular function ( Ejection fraction \< 40%) * Moderate grade of pulmonary disease * Arrhythmia (atrial fibrillation, atrial flutter.. etc.) * body mass index \> 30 or \< 15 kg/m2
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To assess influence of the position change on PVI and other variables(PPV, SVV) | 1.supine position : 5 minute after anesthesia induction with arterial-line insertion 2. 5 min after crystalloid 4 ml/kg loading / 3. modified prone position (baseline) | When position change from supine to modified prone position, to assess the change of PVI and other variables. The correlation of PVI and cardiac output during this change. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| To measure dynamic variables (pulse pressure variation, stroke volume variation and pleth variability index) in modified prone position | 1. Supine position : 5 minute after anesthesia induction with arterial-line insertion 2. 5 minute after a position change to prone 3. before and after fluid loading | Record the data of variables after 5 minute hemodynamic stability without changes of drugs |
Countries
South Korea
Outcome results
None listed