Healthy, Neck Pain
Conditions
Brief summary
This study investigates if/how an experimentally applied neck muscle pain influences head repositioning error in healthy participants.
Detailed description
Healthy volunteers will participate in a single session study with a crossover design. During the study healthy participants will be randomized to either receive a injection of hypertonic saline (painful injection) or isotonic saline (control injection) in a neck muscle. Head repositioning accuracy will be assessed with and without performing a cognitive task.
Interventions
Painful condition: Participants will be injected in a neck muscle with 0.5ml of hypertonic saline (5.8%)
Control condition: Participants will be injected in a neck muscle with 0.5ml isotonic saline (0.9%)
Sponsors
The Danish Rheumatism Association
Aalborg University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Intervention model description
Participants will be randomized to either the painful condition or the control condition first before crossing over to opposite condition.
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy men and women aged 18-50 years * Right handed * Able to speak, read and understand Danish or English * Normal pain free neck and shoulder range of motion
Exclusion criteria
* Pain from the neck or shoulder area * Prior surgery in neck or shoulder * Pregnancy * Drug addiction defined as the use of cannabis, opioids or other drugs * Self reported neurologic, musculoskeletal or mental illnesses
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in head repositioning accuracy | Within session (session lasts approximately 2 hours) | Participants will be blindfolded and asked asked to, from a neutral position, to move the head into full range of motion before returning to to a neutral position again. The difference between the start and end position will be used as an estimate of head repositioning error. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in perceived pain | Within session (session lasts approximately 2 hours) | Pain will be scored using a scale from 0-10 with 0 being no pain and 10 being worst imaginable pain, by drawing on body charts and choosing words from the McGill Pain Questionnaire. |
| Change in perceived performance of head repositioning accuracy test | Within session (session lasts approximately 2 hours) | Likert scores of the perceived difficultness (0=no problems, 1=minimally difficult, 2=somewhat difficult, 3=fairly difficult, 4= very difficult, 5=unable to perform) |
Countries
Denmark
Outcome results
None listed