Cervical Cancer, Pathological Screening Smear
Conditions
Keywords
Endocervical curettage, Kevorkian, Cytobrush, FCV
Brief summary
The recommendations on the method and the realization of the cervico-uterine smears are clear. With regard to performing endocervical curettage, several methods are possible without precise consensus. In general, the Kevorkian curette is widely used. However, it is often reported by doctors and patients that curettage is painful. Some articles show that the cytobrush would be less painful. While keeping a percentage of correct curettage failures, it is sought to show that the cytobrush would improve the comfort of the patient during curettage.
Interventions
DEVICECytobrush
the brush would be inserted in full until the display of the brush in the endocervical canal disappears. A neck quadrant scan (= quarter turn) will be performed from front to back while simultaneously rotating the brush clockwise, for a total of 3 laps. This would represent 4 sweeps per turn, ie 12 sweeps in total
DEVICEKevorkian curette
the colposcopist holds the curette horizontally and scrapes the endocervical canal all the way around. He realizes 1 small firm and linear movement by quarter turn or 4 movements to realize a complete turn. During this act, the curette must remain inside the canal, and during its extraction, care should be taken not to rotate it so as not to spill the collected tissue contained in the basket of the curette. The tissue material thus obtained must be rapidly immersed in formalin
Sponsors
University Hospital, Lille
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
25 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Women followed for a cervical pathology requiring endocervical curettage: * AGC type (glandular cell atypia) with positive HPV test * Frottis ASC-H, LSIL, ASCUS HPV + with non-contributive colposcopy (ZT3)
Exclusion criteria
* Pregnant woman * Women under the age of 25 or over 65 * Stenosis of the neck complete or tight not allowing the possible insertion of a curette (inadequate size cervical orifice and material) * Presence of a vaginal lesion on colposcopic examination
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of sampling failures | once time, Baseline | Unsatisfactory sampling will be defined by a specimen containing \<20 endocervical cells, \<3 epithelial flaps, and one specimen without stroma. |
Secondary
| Measure | Time frame |
|---|---|
| Pain Assessment Using a Visual Analogue Scale (VAS) | once time, Baseline |
Countries
France
Outcome results
None listed