ECG AI-Guided Screening for Low Ejection Fraction

Conditions

Asymptomatic Left Ventricular Systolic Dysfunction (Disorder), Heart Failure

Brief summary

This is a randomized controlled trial (RCT) to test a novel artificial intelligence (AI)-enabled electrocardiogram (ECG)-based screening tool for improving the diagnosis and management of left ventricular systolic dysfunction.

David Rushlow, Ivana T. Croghan, Jonathan Inselman, Tom D. Thacher, Paul A. Friedman et al. (16 authors)

Mayo Clinic Proceedings2022-11-0128 citations

10.1016/j.mayocp.2022.04.008

Provider Perspectives on Artificial Intelligence–Guided Screening for Low Ejection Fraction in Primary Care: Qualitative Study

Barbara Barry, Xuan Zhu, Emma Behnken, Jonathan Inselman, Karen Schaepe et al. (16 authors)

JMIR AI2022-10-1415 citations

10.2196/41940

Artificial intelligence-enabled electrocardiograms for identification of patients with low ejection fraction: a pragmatic, randomized clinical trial.

Yao X, Rushlow DR, Inselman JW, McCoy RG, Thacher TD, Behnken EM, Bernard ME, Rosas SL, Akfaly A, Misra A, Molling PE, Krien JS, Foss RM, Barry BA, Siontis KC, Kapa S, Pellikka PA, Lopez-Jimenez F, Attia ZI, Shah ND, Friedman PA, Noseworthy PA.

2021-05-06248 citations

10.1038/s41591-021-01335-4

ECG AI-Guided Screening for Low Ejection Fraction (EAGLE): Rationale and design of a pragmatic cluster randomized trial.

Yao X, McCoy RG, Friedman PA, Shah ND, Barry BA, Behnken EM, Inselman JW, Attia ZI, Noseworthy PA.

2019-10-2562 citations

10.1016/j.ahj.2019.10.007

Interventions

OTHERAI-enabled ECG-based Screening Tool

A novel artificial intelligence (AI)-enabled electrocardiogram (ECG)-based screening tool for improving the diagnosis and management of left ventricular systolic dysfunction.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* Primary care clinicians who are part of a participating care team that care for adult patients and have the ability to order ECG and TTE (this includes physicians, nurse practitioners, and physician assistants).

Exclusion criteria

* Primary care clinicians working in pediatrics, acute care, nursing homes, and resident care teams.

Design outcomes

Primary

Measure	Time frame	Description
New Diagnosis of Low Ejection Fraction (defined as ejection fraction ≤50%)	Within 90 days	Ejection fraction obtained by echocardiography.

Countries

United States

Outcome results

None listed