Acute Coronary Syndrome, Acute Heart Failure, Heart Failure
Conditions
Brief summary
This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical course of the disease. Data of patients who were hospitalized during the years 2010-2023 with acute coronary syndrome (ACS) and/ or with acute heart failure (AHF) will be collected and analyzed. In a subgroup cohort efficacy and safety of digoxin in patients with acute heart failure triggered by tachyarrhythmia will be evaluated.
Interventions
OTHERmedical chart review
data generated by medical review include Medical history, Medications at presentation, during hospitalization and at discharge, New York Heart Association (NYHA) class, Killip class, Electrocardiographic (ECG) data, echocardiographic data, Interventions (Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft (CABG), Implantable Cardioverter Defibrillator (ICD) implantation, Cardiac Resynchronization Therapy (CRT) Implantation), Outcome Information: all-cause death, HF hospitalizations
OTHERdata generated by direct IT export
data generated by direct IT export include Anthropometric data (age, sex, height, weight), Vital signs, Laboratory data
Sponsors
University Hospital, Basel, Switzerland
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients hospitalized with a primary diagnosis of ACS * Patients hospitalized with a primary or secondary diagnosis of AHF
Exclusion criteria
* Existence of a documented statement of the patient against the scientific use of clinical data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| number of all-cause death | 1 to 8 years after hospitalization | number of all-cause death in patients hospitalized with ACS and AHF during the years 2010-2023. |
| number of HF hospitalizations | 1 to 8 years after hospitalization | number of new HF hospitalizations in patients hospitalized with ACS and AHF during the years 2010-2023 |
| number of cardiovascular death | 1 to 8 years after hospitalization | number of cardiovascular death in patients hospitalized with ACS and AHF |
| number of cardiovascular hospitalizations | 1 to 8 years after hospitalization | number of cardiovascular hospitalizations |
Countries
Switzerland
Contacts
Primary ContactChristian Müller, Prof. Dr.
Backup ContactFiona Nafaa, MD
Outcome results
None listed