Atherosclerosis, Aortic Coarctation
Conditions
Brief summary
Despite aortic coarctation (CoA) repair these patients have cardiovascular complications and coronary artery disease is the most common cause of death.
Detailed description
The aim with this study was to measure intima-media thickness (IMT) and plaques in arteries compared to cardiovascular markers in controls and patients with CoA.
Interventions
Ultrasound measurement
Sponsors
Skane University Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* sex and age-matched controls
Exclusion criteria
* acute and chronic inflammation disease, underlying malignancies and diabetes mellitus.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intima-media thickness | Intima-media thickness will be measured at one time point namely at inclusion. Data will be reported when study is completed, an average of 2 year. | Measurement in mm |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cardiovascular markers | Blood samples will be taken at one time point namely at inclusion. Then biomarkers will be analysed when study is completed. Data will be reported when study is completed, an average of 2 year. | A multiplex platform to analyze circulating blood levels biomarkers was used. |
Outcome results
None listed