Organ Transplantation
Conditions
Keywords
organ transplantation, graft, biological collection.
Brief summary
Increased indications for transplantation continue to worsen the shortage of organs and need the extension of graft sampling criteria and the search for new potential sources of organs. Despite undeniable success in the short term, due to major advances in surgery, medicine and research, transplant recipients continue to face the risk of chronic rejection and long-term complications. The University Hospital Federation FHU SUPORT was created to optimize the chances of success of the organ transplant and improve the quality of life of the transplanted patient. FHU SUPORT 's ambition is based on a translational strategy that presents two priority areas: Axis 1: Optimization, evaluation, conditioning of the donor, graft, recipient Axis 2: Personalized follow-up of the transplanted patient in the short and long term Identifying factors for long-term graft and patient survival through translational research from a common cohort and biological collection will predict transplant rejection, prolong graft function, or improve the patient's care.
Interventions
various blood and urine samples will be collected from the recipient at D0, D7, D14, M1, M3, M6 and M12 and intraoperative bile collection
Sponsors
University Hospital Federation FHU SUPORT
University Hospital, Limoges
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Intervention model description
various blood and urine samples will be collected from the recipient at D0, D1, D3, D7, D14, M1, M3, M6 and M12 and intraoperative bile collection ancillary studies : stools at D0 D7 M1 and M3 will be collected for liver transplant patient
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Male or female over 18 (no age limit) * affiliated to a social security organization * Recipient (s) of a kidney, liver or heart transplant * followed by at least one of the FHU SUPORT centers (Tours, Poitiers, Limoges, Rennes) * having given informed consent to participate in the cohort.
Exclusion criteria
* Patient unable to understand the information given by the investigator * People under the protection of justice
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival of the graft | 12 months |
Countries
France
Contacts
Primary ContactSophie ALAIN, MD
Outcome results
None listed