Depression
Conditions
Brief summary
Pilot study design that operationalizes the multimodal manner of care while evaluating changes in depression symptoms, dysmetria, and balance for medication non-responders.
Detailed description
Pilot study design that operationalizes the multimodal manner of care while evaluating changes in depression symptoms, dysmetria, and balance for medication non-responders. This research will provide an initial first step towards answering the following three research questions: 1. Does a multimodal chiropractic applied clinical neuroscience approach to care affect self-reported symptoms of depression? 2. Does a multimodal chiropractic applied clinical neuroscience approach to care affect dysmetria and balance control in a clinically depressed population? 3. Are changes in dysmetria and balance control correlated with a change in depressive symptoms.
Interventions
PROCEDUREChiropractic Applied Clinical Neuroscience
Chiropractic Applied Clinical Neuroscience makes use of chiropractic care in addition to application of therapies designed to stimulate multisensory reintegration and cerebellar coordination. The multisensory reintegration and cerebellar therapies make use of the body's own sensory receptors as a target, with the purpose of realigning the brain's interpretation of different afferent signals. Observation of motor and autonomic output patterns during and after sensory stimulation afford the clinician real-time feedback, providing for adaptation of the sensory based protocol.
Sponsors
Life University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* You are over the age of 18. * You have been diagnosed with depression. * You are currently taking medication for depression or have previously taken medication. * You have been or were on your depression medication for at least 3 months. * You feel/felt that the medication is/was not helping.
Exclusion criteria
* Had a lifetime history of severe neurologic or mental illness (e.g. schizophrenia or substance abuse) * Are pregnant * Have pending litigation or a recent history of spinal fracture, metastatic cancer, chiropractic care within the past month * Present with contraindications to chiropractic care
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| P300 Auditory Evoked Potential task | 20 minutes | Time-locked electroencephalography recording of the P300 event related potential. P300 testing involves placing electrodes on the participant's scalp while the individual is listening to a series to two different tones through headphones. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Shift Balance Platform | 10 minutes | Limits of stability test: For the limits of stability test the participant will be asked to lean forward, backward, left, and right. The participant will lean slowly in each direction at a self-determined speed and to a point where he or she feels is the maximum leaning distance without falling. The tests should take about 2 minutes but will vary based on the participant. |
Countries
United States
Outcome results
None listed