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The Impact of Inspiratory Muscle Strength Training

The Impact of Inspiratory Muscle Strength Training on Weaning Parameters Among Ventilator-dependent Patients

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03997214
Acronym
IMT
Enrollment
43
Registered
2019-06-25
Start date
2018-06-15
Completion date
2018-12-31
Last updated
2019-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator Dependency

Brief summary

The study is a pre-post test with quasi experimental design. Forty-two intubated-adults who had been mechanically ventilated for more than 21 days were selected on the basis of inclusion criteria in respiratory care ward. These patients were classified equally into study group and control group. The experimental group received the intervention of respiratory muscles training 5 times/ a week for 6 weeks. The control group received normal care. The intervention was adjusted trigger sensitivity to 10% of the first recorded Maximal Inspiratory Pressure at the start of training, then increased the ventilator trigger sensitivity and training duration weekly. The largest of ventilator trigger sensitivity is not over 40% of the initial Maximal Inspiratory Pressure and the timing of training duration is no longer than 30 minutes.

Interventions

The experimental group received the intervention of inspiratory muscles training 5times/week for 6 weeks, 5days/ per cycle; the patients stayed in the semi-recumbent position, recorded the initial/first measurement of MIP. The trigger sensitivity was adjusted to 10% of the first recorded MIP at the start of training, then reducing the ventilator trigger sensitivity and training duration weekly.

Sponsors

Fooyin University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Age \>20y/o * Vital signs stable * MIP \<20cmH2O * Ventilator FiO2\<40%, PEEP \<8 * Ventilator mode:PSV or SIMV

Exclusion criteria

* Patient or family refuse

Design outcomes

Primary

MeasureTime frameDescription
Maximal inspiratory pressure7 weeksa measure of the strength of inspiratory muscles, measurement by cmH2O.
Tidal volume7 weeksthe volume of air that is transported into and out of the lungs with each respiratory cycle, measurement by mL per inspiration
Minute ventilation volume7 weeksthe quantity of air moved into and out of the lungs in a minute, measurement by l.min
Rapid shallow breathing index7 weeksthe ratio of respiratory frequency to tidal volume (f/VT)
Oxygenation index.7 weeksOxygenation index OI = FiO2 x 100 x M AP/PaO2, where FiO2 is the fraction of inspired oxygen, MAP is the mean airway pressure, and PaO2 is the partial pressure of oxygen in arterial blood, calculated at the end of the first day of standardized preoperative stabilization

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026