Cannabis, Electromyography, Myofascial Pain, Temporomandibular Disorder
Conditions
Keywords
temporomandibular disorder, Cannabis, Electromyography, Masticatory muscles, Topical application
Brief summary
Evaluation of myorelaxant effect of cannabis cream.compared to placebo cream in topical skin application in patients with TMD
Detailed description
Cannabis sativa has a very wide application in various fields of medicine. In patients with temporomandibular disorder, especially with myofascial pain of masticatory muscles there is a special need to seek an effective pain therapy and muscle relaxing methods. Patients with TMD suffer from chronic pain and depression, cannabis topical skin application therapy seems promising in that field. Patients attending The Department of TMD in Zabrze, Polska were randomly divided into two groups: experimental and placebo. sEMG activity values were compared during 14 days therapy with cream. Positive results were obtained confirming the efficacy of the cannabis cream used in the study, compared to placebo.
Interventions
COMBINATION_PRODUCTCannabis Cream
Topical, bilateral skin application of cannabis cream with self-massage of masseter muscles
COMBINATION_PRODUCTPlacebo Cream
Topical, bilteral skin application of placebo cream with self-massage of masseter muscles
Sponsors
Medical University of Silesia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Masking description
double blind study: for patients and researchers
Intervention model description
two groups parallel study: experimental and control group
Eligibility
Sex/Gender
ALL
Age
22 Years to 27 Years
Healthy volunteers
Yes
Inclusion criteria
The inclusion criteria were as follows: 1. Patient agreement to participate into the research study 2. Age ≥22 and ≤ 27 3. Good general health, 4. Temporomandibular disorder-positive RDC/TMD examination for group Ia and Ib 5. Presence of all teeth (with the exception of the third molars) The
Exclusion criteria
were: 1. Cannabis cream/ placebo cream allergy 2. Hypersensitivity to substances to be used in the study 3. Skin wounds with skin surface discontinuation 4. Addiction to cannabis 5. Patients being treated with analgesic drugs and/or drugs that affect muscle function 6. Fixed or removable dental prosthesis 7. Disease or autoimmune disorder associated with generalized muscular tension
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reduction of sEMG activity of masseter muscle | 14 days | Reduction in masseter muscle electromyographic activity |
Countries
Poland
Outcome results
None listed