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Cut-off Values of Muscle Thickness Ratio for Sarcopenia

Cut-off Values and Adjustments for Diagnosing Sarcopenia

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03993405
Enrollment
292
Registered
2019-06-20
Start date
2019-01-01
Completion date
2019-08-09
Last updated
2019-08-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia

Keywords

older people, muscle, ultrasound

Brief summary

The loss of muscle mass is one of the major diagnostic criteria for sarcopenia. Many methods are also used for the definition of sarcopenia. However there is no information about cut-off values in this respect in the literature. Therefore, the aim of this study is to determine the cut-off values of this ratio for confirming the diagnosis of sarcopenia.

Detailed description

Decreases in total skeletal muscle mass are accepted to be necessary for confirming the diagnosis of sarcopenia. Many methods are also used for the definition of sarcopenia. However, ultrasound measurements has a high sensitivity and specify for confirming the diagnosis of sarcopenia. However there is no information about cut-off values in this respect in the literature. Therefore, the aim of this study is to determine the cut-off values of this ratio for confirming the diagnosis of sarcopenia.

Interventions

Ultrasonographic measurement is assessment method to diagnosis of sarcopenia

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes

Inclusion criteria

* To be a volunteer to participate * To be an aged 18-90 years old.

Exclusion criteria

* Walking with assist device * Having a visual deficits * Having an undergone orthopedic surgery * Having a cardiac pacemaker * Having a hypothyroidism, diabetes mellitus, renal/hepatic failure

Design outcomes

Primary

MeasureTime frameDescription
Muscle thickness30 minutesMuscle thickness in millimeters by Ultrasound.
Skeletal muscle mass2 minutesSkeletal muscle mass will be evaluated by bioelectrical impedance analysis.The unit of measure is kg.

Secondary

MeasureTime frameDescription
Physical function5 minutesPhysical function will be evaluated by short physical performance scale. The score of this scale range from 0 (worst performance) to 12 (best performance).
Anthropometric assessments5 minutesParticipants waist, hip and calf circumferences will be measured by tape measure. The unit of measure is centimeters.
Muscle strength15 minutesMuscle strength will be evaluated using an isokinetic dynamometer (Biodex Medical Systems, New York, USA). Knee and ankle muscle strength( flexion, extension, dorsiflexion and plantarflexion) will be evaluated. The unit of measure is Nm/kg.
Body mass index1 minuteParticipants' weight and height will be evaluated by electronic weighing and tape measure, respectively. body mass index will be expressed in in kg/ m²
Balance1 minuteTimed up and go test evaluates dynamic balance of participants. The timed up and go test measures the time that a patient needs to stand up from a chair, walk a 3-m distance, come back and sit back on the chair.Timed up and go test measure is second. The lower values indicates the better balance.
Peripheral strength1 minutesThe peripheral (handgrip) strength will be measured with a dynamometer (JAMAR).Three measurements will be taken, whose average of the three measurements will be collected. The unit of measure is kg.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026