Clinical Outcomes for Deep Brain Stimulation

Clinical Outcomes for Deep Brain Stimulation for Parkinson Disease, Tremor, and Dystonia

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03992625

Enrollment

1000

Registered

2019-06-20

Start date

2011-01-03

Completion date

2030-01-01

Last updated

2019-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dystonia, Essential Tremor, Parkinson Disease

Keywords

Deep brain stimulation

Brief summary

The object of this study is to longitudinally collect clinical outcomes of patients receiving deep brain stimulation for movement disorders with the objective of making retrospective comparisons and tracking of risks, benefits, and complications.

Interventions

DEVICEDeep Brain Stimulation

High frequency electrical stimulation of deep brain nuclei for the treatment of movement disorders

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Levodopa responsive Parkinson disease OR * Medically refractory Essential Tremor OR * Medically refractory Dystonia

Exclusion criteria

* Dementia (Mattis Dementia Rating Scale \<130) * Structural abnormalities precluding intracranial surgery

Design outcomes

Primary

Measure	Time frame	Description
UPDRS	Change in UPDRS at 1 year after DBS (from preoperative baseline).	United Parkinson's Disease Rating Scale (global assessment of motor, non-motor, and quality of life associated with symptoms of Parkinson disease). Total scores range from 0-199. Particular emphasis is paid to subsection 3 (motor), where scores range from 0-56.

Countries

United States

Contacts

Primary ContactMwiza Ushe, M.D.

ushem@wustl.edu3143625262

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026