Bone Loss, CGF, Post-operative Wound Healing
Conditions
Brief summary
The aim of the study is to evaluate the influence of CGF application into post-operative soft tissue and bone defects on post-operative complications and wound healing.
Detailed description
The research was conducted in twenty patients with symmetric single tooth qualified to extraction. On one side of dental arch, post-operative region was field with CGF material, while on the other side it was left to normal healing. In both cases pain, swelling, alveolar osteitis, antibiotics and analgesics intake in post-operative period were evaluated in the first, fourth and seventh day after surgery. Wound healing was assessed seven and thirty days after extraction.
Interventions
PROCEDURECGF application
CGF application into post-operative soft tissue and bone defects
Sponsors
Medical University of Lodz
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* no known medical history of abnormal platelet counts, * patients with symmetric teeth qualified for extraction,
Exclusion criteria
* systemic diseases, * pregnancy, * lactation, * drugs known to affect the number or function of platelets, * abnormal platelet counts
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intensity of pain vs. CGF application | 24 hours | In order to evaluate the relationship between intensity of pain after surfery and filling the alveolus with platelet-rich plasma, , NRS (Numeric Rating Scale) pain scale is used. NRS scale, ranges from 0 to 10; where 0 refers to no pain and 10 refers to most severe pain. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of swelling | 24 hours | The presence of swelling was evaluated using zero one system. |
Countries
Poland
Outcome results
None listed