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Remineralization Potential of Ginger and Rosemary Herbals Versus Sodium Fluoride in Treatment of White Spot Lesions

Remineralization Potential of Ginger and Rosemary Herbals Versus Sodium Fluoride in Treatment of White Spot Lesions: A Randomized Controlled Trial

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03990935
Enrollment
60
Registered
2019-06-19
Start date
2019-07-31
Completion date
2020-06-30
Last updated
2019-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

White Spot Lesions

Brief summary

To evaluate the effectiveness of ginger and rosemary herbals versus sodium fluoride in remineralization of incipient enamel caries.

Detailed description

Group 1 (intervention) Ginger and rosemary gel application: First the participant will be asked to brush his/her teeth thoroughly with 1450 ppm fluoride toothpaste (Colgate total healthy clean toothpaste). Then an application of a thin ribbon of this gel to the teeth using a brush. The medication will be left for at least 1 minute. The participant will be asked to spit out the medication after use and not to swallow it. Also the participant will be asked not to rinse his/her mouth, eat, or drink for at least 30 minutes after use to get the best results. Group 2 (control group). Sodium fluoride varnish The fluoride varnish will be bifluorid 10 single use by voco (Germany). It Contains 5 % sodium fluoride (equal to 22,600 ppm fluoride). A thin coat will be applied on the tooth surface by using a brush. 10-20 s are sufficient for the varnish to be absorbed and then dry with air. Participants will be informed that they should not brush their teeth for 12-24 hours after the application and not to eat, or drink for at least 30 minutes after use to get the best results.

Interventions

OTHERginger and rosemary gel

First the participant will be asked to brush his/her teeth thoroughly with 1450 ppm fluoride toothpaste (Colgate total healthy clean toothpaste). Then an application of a thin ribbon of this gel to the teeth using a brush. The medication will be left for at least 1 minute. The participant will be asked to spit out the medication after use and not to swallow it. Also the participant will be asked not to rinse his/her mouth, eat, or drink for at least 30 minutes after use to get the best results.

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
13 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Patient who has just completed a comprehensive orthodontic treatment. * Presence of at least one WSL, DIAGNOdent score (0-20). * Age range between 13 and 35years.

Exclusion criteria

* Patients with a compromised medical history. * Severe or active periodontal disease * Patients with developmental hypo-calcified lesions

Design outcomes

Primary

MeasureTime frameDescription
(white spot lesion progression)T0 Baseline T1 1 months T2 3 months T3 6 monthsThe change in the lesion fluorescence will be evaluated using diode laser fluorescence device (Diagnodent).

Countries

Egypt

Contacts

Primary Contactmanaa
sara.mohamed.manaa@hotmail.com00201022484815
Backup Contactmanaa
00201024710307

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026