Stress Disorder, Post Traumatic
Conditions
Keywords
effective connectomic neurological soft signs
Brief summary
PTSD is a debilitating mental disorder that may develop after experiencing or witnessing a life-threatening event. With appropriate care, treatment efficiency is variable and around 20% of the patients do not respond to psychological treatment. Complementary treatments are needed. as PTSD implied autonomic nervous system (ANS) dysfonction, complementary treatment focusing on ANS regulation, as welle as musicotherapy, may have an interest.
Detailed description
The aim is to evaluate the impact of musicotherapy on PTSD symptoms, and severity using a RCT Symptoms will be evaluated using questionaires (PCL and quality of life) severity will be measured using neurological soft signs assessment, connectomic functions and ANS regulation
Interventions
OTHERmusicotherapy
receptive music therapy. The musical style of the session was chosen by the patient. The validated 'U' technique was employed.
Sponsors
Institut de Recherche Biomedicale des Armees
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
musicotherapy versus waiting list
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* PTSD
Exclusion criteria
* neurological diseases * addiction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in PTSD symptoms | change from PTSD symptoms at two months and at six months | questionnaire Posttraumatic CheckList 5 (PCL5; threshold =33) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in effective connectomic | change from effective connectomic at two months and at six months | Magnetic Resonance Imaging |
| Autonomous nervous system regulation | change from Autonomous nervous system regulation at two months and at six months | heart rate variability during 5 min at rest |
| change in biological stress | change from biological stress at two months and at six months | blood cytokines, BDNF |
| change in neurological soft signs | change from neurological soft signs at two months and at six months | questionnaire EPSID Psychomotor assessment scale of neurological soft signs no threshold |
Countries
France
Outcome results
None listed