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Effects of Volatile and Intravenous Anesthetics on Pupillary Function

Comparison of Effects of Volatile and Intravenous Anesthetics on Pupillary Function During General Anesthesia in Children; a Prospective Observational Study.

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03987529
Enrollment
22
Registered
2019-06-17
Start date
2020-08-12
Completion date
2021-02-28
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pupillary Functions, Abnormal

Brief summary

To compare of effects of volatile and intravenous anesthetics on pupillary function during general anesthesia in children

Detailed description

The investigator will measure the pupillary function with pupillometry during general anesthesia with volatile or intravenous anesthetics in children.

Interventions

OTHERsevoflurane

volatile anesthetic

OTHERpropofol

intravenous anesthetic

Sponsors

Seoul National University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
3 Years to 12 Years
Healthy volunteers
No

Inclusion criteria

* Pediatric patients undergoing general anesthesia

Exclusion criteria

* If injection of any agents that can change pupil size or index * Any severe side effects, adverse drug reaction

Design outcomes

Primary

MeasureTime frameDescription
NPi1hour afer skin incisionNeurological Pupil index

Secondary

MeasureTime frameDescription
%CH1. Stage of loss of consciousness after induction with bolus propofol 2. Before and after tracheal intubation 3. Skin incision 4. 1hour afer skin incision 5. Just before extubation% change of pupil size
CV1. Stage of loss of consciousness after induction with bolus propofol 2. Before and after tracheal intubation 3. Skin incision 4. 1hour afer skin incision 5. Just before extubationConstriction Velocity
DV1. Stage of loss of consciousness after induction with bolus propofol 2. Before and after tracheal intubation 3. Skin incision 4. 1hour afer skin incision 5. Just before extubationDilation Velocity
NPi1. Stage of loss of consciousness after induction with bolus propofol 2. Before and after tracheal intubation 3. Skin incision 4. 1hour afer skin incision 5. Just before extubationNeurological Pupil index

Countries

South Korea

Contacts

Primary ContactSang-Hwan Ji, M.D., M.S.
taepoongshin@gmail.com+82-2-2072-3661

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026