Exploration of Angiogenesis in Decompensated Developmental Venous Abnormalities

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03986853

Acronym

Explor-AVD

Enrollment

Registered

2019-06-14

Start date

2018-01-11

Completion date

2021-01-11

Last updated

2022-08-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Developmental Venous Anomaly

Brief summary

The purpose of our study is to demonstrate by blood samples in situ in the vascular lesion (performed during any cerebral catheterization for an embolization of arteriovenous malformation) the existence of angiogenic growth factors and inflammatory factors that would confirm the decompensation of venous ischemia.

Interventions

PROCEDUREBlood sampling

Blood sampling under general anesthesia

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Main Inclusion Criteria: * Presenting a DVA requiring hyperselective catheterization * Having sign an informed consent form

Exclusion criteria

* Presenting a contraindication to the realization of hyperselective cathterism

Design outcomes

Primary

Measure	Time frame	Description
Assessment of angiogenic and inflammatory growth factors	1 day	The 1st factor studied is VEGF-A

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026