The Vascularity Changes of Scars With Laser Therapy

The Vascularity Changes of Scars With Receiving Pulsed Dye Laser

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03986346

Enrollment

Registered

2019-06-14

Start date

2019-05-31

Completion date

2020-02-27

Last updated

2020-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertrophic Scar

Keywords

hypertrophic scar, pulsed dye laser

Brief summary

The purpose of this study is to explore the effects of pulsed dye laser on managing scar vascularity and thickness.

Detailed description

The pulsed dye laser is increasingly used in clinical settings to manage scars and shows promising outcomes.The pulsed dye laser targets at micro-vascular structures in scar tissues. This study aims to explore the vascularity changes in scars with pulsed dye laser during the scar formation process.

Interventions

DEVICEpulsed dye laser

The scar will receive PDL 585 nm using a 7 mm spot size. First treatment will be within 1 year post injury.

OTHERstandardized care

the scar will receive standardized care such as scar massage.

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

16 Years to 70 Years

Healthy volunteers

Inclusion criteria

* scars caused by burn injury or related trauma; * wound healing days over 3 weeks; * days post injury less than 1 year; * ability and willingness to comply with all the treatment and assessment procedures.

Exclusion criteria

* history of steroid injection or graft surgery; * history of keloid scarring; * open wound or active infection; * conditions that affect wound healing, such as diabetes mellitus.

Design outcomes

Primary

Measure	Time frame	Description
scar erythema	3 months	Dermoscopy captures the scar photo and measures degrees of scar erythema.
scar blood flow	3 months	Ultrasound measures blood flow in scar tissues
scar thickness	3 months	Ultrasound measures scar thickness.

Secondary

Measure	Time frame	Description
patient and observer scar assessment scale (POSAS)	3 months	The POSAS measures scar vascularity, pigmentation, pigmentation, thickness, relief, pliability and surface area. Every parameter ranges from 1 to 10, and higher score indicates worse scar performance in that parameter. The total score of POSAS is calculated by summing all the parameters' scores.

Countries

China, Hong Kong

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026