ST Elevation Myocardial Infarction
Conditions
Brief summary
Estimated glomerular filtration rate(eGFR) is significantly reduced in patients with ST-segment elevation myocardial infarction (STEMI). The aim of this study is to research that the incidence of adverse cardiovascular events (MACE) in patients with ST-segment elevation myocardial infarction is significantly higher when the glomerular filtration rate below a certain value.
Detailed description
The investigators retrospectively analyzed the clinical data of 1157 patients with ST-segment elevation myocardial infarction. In-hospital adverse cardiovascular events (MACE) was defined as: cardiac arrest, cardiac rupture, malignant arrhythmia, and cardiac death. All the patients were divided into 3 groups according to the patient's estimated glomerular filtration rate(eGFR) (eGFR≥90ml/min/1.73m2; 90ml/min/1.73m2\>eGFR≥60ml/min/1.73m2; eGFR\<60ml/min /1.73m2). COX regression analysis and K-M survival curves are used to calculate the correlation between eGFR and in-hospital MACE.
Interventions
None listed
Sponsors
Dongying Zhang
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
24 Years to 93 Years
Healthy volunteers
Yes
Inclusion criteria
* 1.Patients with STEMI 2.Patients from whom informed consent has been properly obtained in writing prior to start of the trial
Exclusion criteria
* 1.Patients with previous myocardial infarction, congenital heart disease 2.Patients with liver disease, and renal failure 3.Patients with immunologic disease, malignant tumors, pregnancy, infection caused by various pathogens, chronic inflammatory disease, trauma.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| major adverse cardiac events | The median time of 7 days | Relationship between reduced eGFR and in-hospital MACE |
Outcome results
None listed