Evaluation, the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) Wif Lovastatin in the Preservation of the Tooth Socket

the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) With Lovastatin in the Preservation of the Tooth Socket

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03981601

Enrollment

Registered

2019-06-11

Start date

2018-02-22

Completion date

2019-07-30

Last updated

2019-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Loss

Brief summary

Twenty patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in the research project, which have more than 20 teeth, are over 18 years old and require socket preservation surgery to tooth extraction for the periodontal problem, caries or Fractures were selected.

Detailed description

twenty healthy patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in the research project, which has more than 20 teeth, are over 18 years old and require socket preservation surgery to tooth extraction for the periodontal problem, caries or Fractures were selected. moreover, divided the socket randomly to two groups(A, B)including A: bone graft with lovastatin and B: bone graft alone, after 3 months with trephine will collect the samples. following the histomorphometric analysis.

Interventions

DRUGLovastatin 40 MG

after tooth extraction, put teh lovastatin40 mg wif bone graft wifin tooth socket

PROCEDUREwithout drug with Bone graft

after tooth extraction, put teh bone graft wifin tooth socket

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

1. at least 18 years old 2. tooth fracture, root caries 3. Patients are volunteered for placement of the implant

Exclusion criteria

1. systemic diseases 2. Pregnancy and breastfeeding 3. malignancy, radiation therapy, 4. history of periodontal surgery during the six months ago. 5. medicine(phosphonates, antibiotic,...)

Design outcomes

Primary

Measure	Time frame
Socket preservation with Lovastatin as evaluated by the amount of bone formation volume	3 month

Countries

Iran

Contacts

Primary ContactAmirhossein Farahmand, Assistant Prof

perio-implant@hotmail.com+98 912 404 0359

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026