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Pulmonary Impacts of Anaesthetic Modalities Evaluated by Ultrasound

Pulmonary Impacts of Anaesthetic Modalities Evaluated by Ultrasound: A Prospective Study in Scheduled Knee Arthroplasty

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03978169
Acronym
PULCHO-KNEE
Enrollment
99
Registered
2019-06-07
Start date
2018-12-13
Completion date
2020-11-30
Last updated
2019-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Keywords

anaesthetic modality, Lung

Brief summary

A prospective, observational, monocentric study aimed at identifying ultrasound changes in anaesthesia on the pulmonary parenchyma after knee arthroplastic surgery using the LUS score in the preoperative, immediate post-operative (D0) and late post-operative (D1) periods.

Detailed description

Post-operative pulmonary complications are responsible from morbidity and mortality close to cardiovascular complications. Perioperative and post-operative respiratory changes are secondary to anaesthesia (general anaesthesia, elongated position, tidal volume) and to surgery in particular abdominal and cardiothoracic surgery. Several risk factors related to patients were identified: age, ASA score\> 2, functional dependence, chronic obstructive pulmonary disease, congestive heart failure, obesity, smoking. Pulmonary ultrasound is a simple and rapid means of monitoring, widely used in resuscitation and developing in anaesthesia. The hypothesis of the study is that anaesthesia and / or ventilation is responsible for lung lesions observable by ultrasound from the recovery room, even after extra-thoracic surgeries. To do this, it will perform 3 pleuro-pulmonary ultrasound scans, preoperatively on the day of surgery, post-operatively in the recovery room and the day after surgery. LUS score will be calculated. Preoperative data (morphology, comorbidities), preoperative (ventilation, filling, position, type of anaesthesia - general anaesthesia with intubation or laryngeal mask, spinal anaesthesia- , type of surgery) and postoperative data (constants, oxygen therapy, complications) will be collected.

Interventions

three pleuro-pulmonary ultrasound scans will be performed, preoperatively on the day of surgery, post-operatively in the recovery room and the day after surgery

Sponsors

University Hospital, Toulouse
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patient undergoing scheduled primary knee arthroplasty : * Partial knee replacement surgery * Total knee replacement surgery • Type of Anaesthesia * General anaesthesia with orotracheal intubation * General anaesthesia with laryngeal mask * Spinal anaesthesia * Major Patient * Oral non opposition collected after oral information of the study

Exclusion criteria

* Refusal to participate * Preoperative pleural pathology (pleural effusion, pleural symphysis) * Pregnancy * Patient under authorship or curators * non-affiliation to a social security scheme

Design outcomes

Primary

MeasureTime frameDescription
lung lesions by the anaesthetic and operative management after knee replacement surgery10 minutes before surgeryDescribe lung lesions by the anaesthetic and operative management after knee replacement surgery

Countries

France

Contacts

Primary ContactFabrice FERRE, MD
ferre.f@chu-toulouse.fr05 61 77 99 88
Backup ContactLAETITIA BOSCH, MD
bosch.l@chu-toulouse.fr05 61 77 99 80

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026