Pomegranate Juice Effect on Oxidative Stress in Infertile Women During IVF Treatment

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03978013

Enrollment

Registered

2019-06-06

Start date

2019-09-01

Completion date

2021-12-01

Last updated

2019-06-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PCOS, Endometriosis, Advised Maternal Age, Male Factor Infertility

Brief summary

tTe investigators estimate pomegranate supplementation effect on oxidative stress in infertile women with PCOS, endometriosis and advanced maternal age during IVF treatment. The primary aim is to compare the obtained oxidative stress markers in follicular fluid with pomegranate supplementation vs control.

Interventions

OTHERPomegranate juice

Pomegranate juice

OTHERApple juice

Apple juice

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Masking description

Pomegranate and control juice will be provided by Primor Company, Hadera, Israel. Control juice has similar color and test but do not include pomegranate.

Intervention model description

RCT

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients undergo IVF treatment with diagnosis of PCOS/Endometriosis/MF or AMA

Exclusion criteria

* Patients who do not meet the inclusion criteria, as above

Design outcomes

Primary

Measure	Time frame	Description
Cytokines levels in follicle fluid	2 weeks	Cytokines (pg/mL) will be mesured by elisa.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026