ICU Patients, New Onset Atrial Fibrillation
Conditions
Keywords
New onset atrial fibrillation, Paroxystic atrial fibrillation, ICU patients, Rate control, Rhythm control
Brief summary
The primary purpose of the study is to evaluate treatment of new onset atrial fibrillation in french ICU.
Detailed description
Atrial fibrillation (AF) is a common arrhythmia in the ICU and is associated with significant morbidity. However, curative treatment remains unclearly established. In fact, there are no specific recommendations for new onset atrial fibrillation in ICU and only few studies have assessed this topic. The PAF-ICU trial is an observational, prospective, multicenter, transversal trial. The main objective is to evaluate the management of paroxytic atrial fibrillation that occur in ICU. The investigators want to document 2500 episodes of paroxystic atrial fibrillation in 50 ICU centers. In each center, the episodes are included consecutively until the required 50 episodes are obtained for each center. A patient can present several episodes and each episode can be included in the study. A new episode is considered as such if it occurs more than one hour after the previous episode. The follow-up period for each patient corresponds to the ICU stay.
Interventions
None listed
Sponsors
French Society of Anesthesia and Intensive Care Medecine
University Hospital, Clermont-Ferrand
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \> 18 years * Patient hospitalized in ICU * New onset atrial fibrillation
Exclusion criteria
* Age \< 18 years * Parturient or breast-feeding woman * Persistent or permanent atrial fibrillation * Patients after cardiovascular or thoracic surgery * Patients with therapeutic limitations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Management of Atrial Fibrillation | ICU stay (until 28 days) | All types of therapeutics used to manage atrial fibrillation are collected |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blood pressure | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | Blood pressure. Unit : Millimeters of mercury |
| Heart rate | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | Heart rate. Unit : beats per minute |
| Cardiac output | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | Product of the heart rate (HR) and the stroke volume (SV), which is the volume of blood pumped from the ventricle per beat. Unit : L/min. |
| Cardiac rhythm status | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | Type of rhythm : Normal (sinus rhythm), Atrial Fibrillation, Other disturbance |
| Vasopressors | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | Type of vasopressors used |
| Stroke | ICU Stay up to 28 days | Occurrence of stroke during ICU stay |
| ScvO2 | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | Venous saturation. Unit : percentage |
Countries
France
Outcome results
None listed