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Evaluation of Diaphragmatic Function After Bi-pulmonary Transplantation

Evaluation of Diaphragmatic Function After Bi-pulmonary Transplantation

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03977597
Acronym
DIATRIB
Enrollment
60
Registered
2019-06-06
Start date
2019-01-03
Completion date
2021-01-03
Last updated
2019-06-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Transplant, Diaphragmatic Function

Keywords

lung transplant, diaphragm evaluation, ultrasound

Brief summary

A current complication after lung transplantation is diaphragmatic dysfunction. These dysfunction result to several factors: duration of mechanical ventilation, chest tube, atelectasis, denutrition, phrenic nerve injury during surgical dissection… Only monocentric and retrospective studies collected diaphragmatic paralysis after lung transplant are published. The incidence of diaphragmatic paralysis in post-operative lung transplantation varies from 3.2% to 16.8%. The main hypothesis of the study is to defined the incidence of diaphragmatic dysfunction in post-operative lung transplantation.

Interventions

None listed

Sponsors

Centre Chirurgical Marie Lannelongue
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years

Inclusion criteria

* Adults (≥ 18 years old) * Admitted for intensive care that can be spontaneously ventilated after bi- pulmonary transplantation

Exclusion criteria

* Minor patient * Ventilated patients less than 24 hours * patients in controlled ventilation

Design outcomes

Primary

MeasureTime frameDescription
incidence of diaphragmatic disorders (paralysis, severe and moderate dysfunction) in the post-operative period of bi-pulmonary transplantation21 daysincidence of diaphragmatic disorders (paralysis, severe and moderate dysfunction) in the post-operative period of bi-pulmonary transplantation

Countries

France

Contacts

Primary ContactThibaut GENTY, MD
t.genty@hml.fr0140942260

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026