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Total Wrist Denervation: Survival Study and Functional Outcomes

Total Wrist Denervation: Survival Study and Functional Outcomes

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03977389
Acronym
DTDPESERF
Enrollment
63
Registered
2019-06-06
Start date
2018-03-20
Completion date
2018-03-30
Last updated
2020-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Survival, Wrist Arthritis

Keywords

Long-term result, Denervation

Brief summary

The purpose of the study is to evaluate the long-term effectiveness of total wrist denervation on pain by assessing the surgery survival. The residual functional wrist's quality and the patients' satisfaction will also be evaluate.

Detailed description

The degenerative diseases of the wrist are numerous and include both post-traumatic osteoarthritis lesions and inflammatory diseases. In any case, one of the main reasons for consultation is pain. In case of inefficiency of a well-conducted medical treatment (splints, anti-inflammatories, infiltrations), surgical management remains difficult because of the multitude of treatments that can be offered: partial or total arthrodesis of the wrist, prosthetic arthroplasties, pyrocarbon implants or proximal row carpectomy. But these treatments are heavy and can potentially be sources of complications such as stiffness, loss of strength or progressive wear of the implant. Total wrist denervation is an alternative since 1966. The original technique follows an anatomical study of the innervation of the upper limb. This technique has been proven to significantly improve pain without major after effects. Several teams demonstrated a decrease in pain associated with conserved strength and mobility, but few studies have studied the long-term results of this technique, especially on the absence of residual pain. The purpose of this study is to evaluate the long-term effectiveness of denervation on pain by assessing the surgery survival, the residual functional wrist's quality and the patients' satisfaction.

Interventions

PROCEDURETotal wrist denervation

Study of the files

Sponsors

University Hospital, Brest
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* patient undergoing total wrist denervation between January 1995 and December 2013 at Brest CHRU, performed by the same senior surgeon

Exclusion criteria

* patient who had another intervention at the same time (confounding factor) * refusal expressed by the patient to participate in the study

Design outcomes

Primary

MeasureTime frameDescription
survival over timefrom date of surgery until the date of first documented failure (surgical revision; pain > 3), assessed up to the inclusion dateduration (in years) of absence of surgical revision, and residual pain \< or = 3 on a pain numerical scale (0 to 10, WHO criteria for mild pain)

Secondary

MeasureTime frameDescription
surgery survival over timefrom date of surgery until the date of documented failure (surgical revision), assessed up to the inclusion dateduration (in years) of absence of surgical revision
residual painat the inclusion datenumeric pain rating scale (between 0 to 10; 0 equal no pain; 10 equal worst pain imaginable)
residual functional wrist's qualityat the inclusion dateResult of the DASH (Disabilities of the Arm and Shoulder Disabilities) score (between 0 to 100; 0 equal better result; 100 equal worst result)
patients' satisfaction (1)at the inclusion dateanalogue scale between 0 to 10 at the last follow-up (0 equal minimum; 10 equal maximum)
patients' satsfaction (2)at the inclusion dateanswer to would you repeat this procedure again?

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026