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Effect of Open-placebo Intervention on Cycling Performance

The Effect of an Open-placebo Intervention on Cycling Time-trial Performance

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03977246
Enrollment
28
Registered
2019-06-06
Start date
2018-05-01
Completion date
2018-09-30
Last updated
2019-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise Performance

Brief summary

This study evaluates the effect of an open-label placebo intervention on cycling time-trial performance.

Detailed description

This study investigated the effect of open-placebo on cycling time-trial (TT) performance. Twenty-eight trained female cyclists completed a 1-km cycling TT following a control session or an open-placebo intervention. The intervention consisted of an individual presentation, provided by a medic, in which the concept of open-placebo was explained to the participant, before she ingested two red and white capsules containing flour; 15 min later, they performed the TT. In the control session, the participant sat quietly for 20 min.

Interventions

BEHAVIORALOpen-placebo

Application of the open-placebo intervention

BEHAVIORALControl

Application of the control session

Sponsors

University of Sao Paulo
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Females aged between 18 and 45 years old; * A minimum of one-year training experience in cycling.

Exclusion criteria

* Smokers * Chronic disease * Prior or current use of steroids * Use of creatine in the last 6 months * Use of beta-alanine in the last 6 months

Design outcomes

Primary

MeasureTime frameDescription
Exercise performance20-min following open-placebo interventionChange in 1 km cycling time-trial performance

Secondary

MeasureTime frameDescription
Blood lactateImmediately post-exerciseChange in blood lactate concentration

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026