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Impact of Lung Recruitment Maneuvers on Driving Pressure in Cardiac Surgery

Impact of Lung Recruitment Maneuvers on Driving Pressure in Cardiac Surgery (IMPREMO): Before - After Trial

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03976947
Acronym
IMPREMO
Enrollment
217
Registered
2019-06-06
Start date
2017-05-01
Completion date
2018-02-28
Last updated
2020-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, General, Atelectasis, Cardiac Surgical Procedures, Lung Diseases, Respiration, Artificial

Keywords

Driving pressure, Postoperative pulmonary complications

Brief summary

In anesthesia the incidence of postoperative pulmonary complications is frequent, especially in cardiac surgery where the incidence can reach 10%. Respiratory morbidity in cardiac surgery is favored by multiple factors and is higher compared to anesthesia in general surgery. The prevention of these complications is a major challenge in the management of patients. Influence of driving pressure level on respiratory morbidity was first demonstrated in management of acute respiratory distress syndrome (ARDS) in resuscitation. More recently, this notion has been introduced in anesthesia, with a correlation between increase driving pressure level and increase of post-operative respiratory complications. A method should reduce these levels of driving pressure: performing lung recruitment maneuvers. This technique has been successfully tested in abdominal surgery in particular in a study published by Futier et al.. They systematized and standardized lung recruitment maneuvers and showed a decrease of postoperative pulmonary complications in abdominal surgery. Thus, the realization of lung recruitment maneuvers, already used at the discretion of the practitioner, is now recommended by several teams of experts. The investigators propose in this before-after trial to evaluate variation in driving pressure due to systematic use of lung recruitment maneuvers, observed in patients operated in elective or urgent surgery. The secondary objective is to evaluate their impact on postoperative pulmonary complications.

Detailed description

This is a retrospective, before / after, monocentric trial.

Interventions

None listed

Sponsors

University Hospital, Caen
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Patients receiving elective or urgent cardiac surgery with cardiopulmonary bypass

Exclusion criteria

* Emergency or salvage surgery * Patient under guardianship * Pregnancy

Design outcomes

Primary

MeasureTime frameDescription
Driving pressure variation due to lung recruitment maneuvers1 daycmH2O

Secondary

MeasureTime frameDescription
Incidence of postoperative pulmonary complicationsbaselinepercentage

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026