White Spot Lesion
Conditions
Brief summary
The aim of this study is to evaluate the remineralization potential of pearl powder on early ('white spot') lesions in enamel in orthodontic patients compared to casein phosphopeptide-amorphous calcium phosphate.
Detailed description
The aim of this study is to evaluate the remineralization potential of pearl powder on early ('white spot') lesions in enamel in orthodontic patients compared to casein phosphopeptide-amorphous calcium phosphate. The remineralisation potential will be assessed both visually and by standardised photographic image analysis. the follow up will be up to 12 months.
Interventions
DRUGCpp-Acp
Remineralising agent
OTHERPearl powder
Natural product
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
12 Years to 25 Years
Healthy volunteers
Yes
Inclusion criteria
* Males or females. * Age: 12-25 years old. * Patients with good oral hygiene. * Co-operative patients who show interest to participate in the study.
Exclusion criteria
* Patients with bad oral hygiene. * Lack of patient's approval and compliance. * Presence of abnormal oral, medical, or mental condition. * Patients who are allergic to milk products. * Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical index used for visual evaluation of white spot lesions | 12 months | Scores(0-No visible colour change, 1-Slight white colour change, only visible after air-drying, 2-Slight colour change with certain marked white areas, 3-White consistent colour change, 4-Distinct white colour change) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Digital photographic image analysis | 12 months | Computerised software to analyse the change in the lesion |
Outcome results
None listed