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Artificial Intelligence/Machine Learning Modeling on Time to Palliative Care Review in an Inpatient Hospital Population

The Impact of Artificial Intelligence/Machine Learning (AI/ML) on Time to Palliative Care Review in an Inpatient Hospital Population

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03976297
Enrollment
2231
Registered
2019-06-06
Start date
2019-08-19
Completion date
2020-12-20
Last updated
2020-12-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Palliative Care

Keywords

Machine learning, Artificial Intelligence, Pragmatic Clinical Trial, Healthcare Delivery

Brief summary

Investigators are testing whether machine learning prediction models integrated into a health care model will accurately identify participants who may benefit from a comprehensive review by a palliative care specialist, and decrease time to receiving a palliative care consult in an inpatient setting.

Detailed description

The need for timely palliative care is crucial. Aging patient populations are becoming more complex, often needing care from multiple specialties. There has been a growing mismatch between clinical care and patient preferences particularly with regards to services near end-of-life. Research has shown that that most people prefer to die at home despite the majority dying outside of the home (nursing home or hospital). Given the current model of care and incentives palliative care is considered the care of last resort after all attempts at cure have been exhausted. This delay can lead to sub-optimal symptom management for pain and lower quality of life. As the demand for palliative care increases, policy initiatives and referral triage tools to that lead to quality palliative care services are needed. In 2018 the Mayo Clinic developed a fully integrated information technology (IT) solution focusing on the identification of patients who may benefit from early palliative care review. The tool, known as Control Tower, pulls disparate data sources centered on a machine learning algorithm which predicts the need for palliative care in hospital. This algorithm was put into production as of December 2018 into a silent mode. The algorithm along with other key patient indicators are integrated into a graphical user interface (GUI) which allows a human operator to review the algorithm predictions and subsequently record the operator's assessment. The tool is expected to enhance risk assessment and create a healthcare model in which palliative care can pro-actively and effectively screen for patient need. Anticipated benefits of the approach include improved symptom control and patient satisfaction as well as a measurable impact on inpatient hospital mortality. The overall objective of this study is to assess the effectiveness and implementation of the Control Tower palliative care algorithm into hospital practice by creating a stepped wedge cluster randomized trial in 16 inpatient units. By creating an algorithm that automatically screens and monitors patient health status during inpatient hospitalization, the investigators hypothesize that participants will receive needed palliative care earlier than under the usual course of care. In addition to testing clinical effectiveness study members will also collect data for process measures to assess the algorithm and healthcare performance after translation of the prediction algorithm from a research domain to a practice setting.

Interventions

OTHERControl Tower

A workstation and software tool that extracts medical data from Mayo's data mart and electronic health record, and processes it through a prediction model that determines whether a patient is suited for a palliative care consult.

Sponsors

Mayo Clinic
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Intervention model description

Pragmatic Stepped Wedge Cluster Randomized Trial

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Admitted to Mayo Clinic St. Mary's Hospital and Methodist Hospital during August 19, 2019 - August 19, 2020. * Once a day Monday through Friday, the CT operator selects 12 patients from all of the nursing units that are participating in the trial (whether or not they are currently in the intervention group) with palliative scores of at least 7 (out of 100), i.e., those that are high risk and displayed as red in the CT GUI (unless they are already being seen by palliative care.) * The CT operator chooses the selected patients by looking at the patients in sorted order starting with the highest score and proceeding down the list, evaluating each patient for

Exclusion criteria

. * Once the CT operator identifies 12 appropriate patients or once they reaches the end of the high-risk patients (score of 7 or higher) they stop.

Design outcomes

Primary

MeasureTime frameDescription
Timely identification for need of palliative care12 monthsMeasured as time in hours to the electronic record of consult by the palliative care team in the inpatient setting.

Secondary

MeasureTime frameDescription
The number of inpatient palliative care consults12 monthsMeasured by the rate of palliative care consults in the inpatient units of interest
Timely identification for need of palliative care per unit12 monthsMeasured as time in hours to the electronic record of consult by the palliative care team in the inpatient setting for each of the 16 nursing units.
Transition time to hospice-designated bed12 monthsFor all patients with Medicare insurance the time until transferred to a hospice-designated bed from admission.
Time to hospice designation12 monthsMeasured as time in hours to the electronic record of consult by the hospice care team in the inpatient setting.
Emergency Department visit within 30 days of discharge12 monthsMeasured by the number of study participants who upon discharge from the inpatient setting are readmitted to the Emergency Department at any Mayo Clinic facility within 30 days.
Hospitalization or readmission within 30 days of discharge12 monthsMeasured by the number of study participants who upon discharge from the inpatient setting are readmitted to an inpatient unit at any Mayo Clinic facility within 30 days (excluding transfers and planned readmits).
ICU transfers12 monthsMeasured by the number of study participants who transferred to a intensive care unit during their inpatient stay.
Ratio of inpatient hospice death to non-hospice hospital deaths12 monthsMeasured by the number of deaths of study participants in hospice designated beds by the number of deaths in non-hospice beds.
Rate of discharge to external hospice12 monthsMeasured by the number of participants whose electronic health record indicates discharge to external hospice.
Inpatient length of stay12 monthsMeasured by the difference between admission to first unit to discharge from hospital for all study participants.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026