Comparison of Oxygen Adminstration by Nasal Cannula and High Flow Cannula During Bronchoscopy

Oxygen Administration During Bronchoscopy in Children, High Flow and Common Nasal Cannula: a Randomized Controled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03976167

Enrollment

108

Registered

2019-06-05

Start date

2015-11-10

Completion date

2019-02-28

Last updated

2019-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Disease

Keywords

Children, Desaturations, Bronchoscopy, Oxygen, High flow oxygen

Brief summary

Randomized controled trial to compare oxygen desaturation during fiberoptic bronchoscopy using oxygen administered with nasal prongs and high flow nasal cannula. Drops in oxygen saturation are frequent during bronchoscopy and limit the procedure compromising patient security. The investigator's aim is to contribute to select better way of oxygen administration which could prevent desaturations during bronchoscopy in children.

Interventions

DEVICEOxygen administration with Common nasal cannula

Oxygen administration during elective flexible bronchoscopy in children with high flow nasal cannula with inspired oxygen fraction 1.

DEVICEOxygen administration with high flow nasal cannula, device Airvo2 Fisher and Pykel

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

29 Days to 16 Years

Healthy volunteers

Inclusion criteria

* elective flexible bronchoscopy

Exclusion criteria

* admitted in Neonatal intensive care * previous respiratory support: oxygen any device, non invasive or invasive ventilation * patient who may benefit with continuous positive pressure during procedure

Design outcomes

Primary

Measure	Time frame	Description
Oxygen desaturation	Trough study completion, an average of 2 years	Number of patients with Oxygen saturation under 94% during bronchoscopy

Secondary

Measure	Time frame	Description
Moderate oxygen desaturations	Trough study completion, an average of 2 years	Number of patients with Oxygen saturation \< 94% and \> 90 %
Severe oxygen desaturations	Trough study completion, an average of 2 years	Number of patients with Oxygen saturation\< 90%
Tachypnea	Trough study completion, an average of 2 years	Number of patients with Breath rate more than p95 fore age for more than 30 seconds
Apnea	Trough study completion, an average of 2 years	Number of patients with Breath rate 0 for more than 20 seconds or recure intervention
Bradycardia	Trough study completion, an average of 2 years	Number of patients with Heart rate less than p5 forte age for more than 20 seconds

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026