Stroke
Conditions
Brief summary
To test the capacity of healthy and chronic stroke patients to learn and retain a complex bimanual motor skill, trained on the neurorehabilitation robot REAplan (R) (bimanual version).
Detailed description
Over 3 consecutive days, healthy individuals and chronic stroke patients (1) will be evaluated and (2) will train on the neurorehabilitation robot REAplan(R). They will practice several tasks on the robot REAplan (R) (bimanual version), requiring either movements with the affected arm (unimanual tasks) and complex, coordinated movements with both arms (bimanual tasks). In addition, several classical clinical scales and tests will be used to evaluate overall motor-sensory-cognitive functions (clinical tests, questionnaires, ...).
Interventions
DEVICEBimanual motor skill learning with the REAplan(R) rehabilitation robot
REAplan(R) rehabilitation robot : training to perform complex, coordinated, bimanual movements
Sponsors
Université Catholique de Louvain
University Hospital of Mont-Godinne
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Intervention model description
Evaluation of bimanual motor skill learning Motor skill learning with a rehabilitation robot
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
STROKE PATIENTS : Inclusion Criteria: * having a chronic stroke (\>6 months) * aged 18-90 years * with demonstrate a stroke lesion on brain imaging.
Exclusion criteria
* difficulty in understanding or executing commands * drug/alcohol abuse * severe aphasia / cognitive deficits interfering with study * inability to voluntarily move the affected arm (i.e. complete paralysis of the arm) * multiple strokes / dementia / psychiatric condition * botulinum toxin injections (to be evaluated) HEALTHY INDIVIDUALS : Inclusion Criteria: \- 18-90 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| bi-SAT, bimanual Speed/Accurady Trade-off measured by the REAplan robot | change between baseline (Day 1) and after training (Day 3) | bimanual Speed/Accurady Trade-off: mathematical computation of the relationship bewteen speed and accuracy |
| bi-CO, bimanual Coordination factor measured by the REAplan robot | change between baseline (Day 1) and after training (Day 3) | bimanual Coordination factor, mathematical measure of the phase coherence between speeds of both arms |
| bi-Force, bimanual Coordination factor measured by the REAplan robot | change between baseline (Day 1) and after training (Day 3) | bimanual forces, forces exerted in the wrong direction by each arm (Newtons) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| bi-smoothness on bimanual REACHING (REAplan robot) | change between baseline (Day 1) and after training (Day 3) | Smoothness of movement : Spectral Arc Length (SPARC) |
| bi-error on bimanual REACHING (REAplan robot) | change between baseline (Day 1) and after training (Day 3) | Error in centimeres or degrees during bimanual reaching |
| bi-SAT on bimanual REACHING (REAplan robot) | change between baseline (Day 1) and after training (Day 3) | bimanual Speed/Accurady Trade-off: mathematical computation of the relationship |
| whole-hand GF | change between baseline (Day 1) and after training (Day 3) | whole-hand Grip Force (GF) measured with a dynamometer, 3 trials/hand) |
| Visual Analog Scale for fatigue (VAS fatigue) | change between baseline (Day 1) and after training (Day 3) | Visual Analog Scale to evaluate fatigue = a psychometric response scale which can be used in questionnaires. It is a measurement instrument for subjective characteristics or attitudes that cannot be directly measured. When responding to a VAS item, respondents specify their level of agreement to a statement by indicating a position along a continuous line between two end-points. Range : 0- 10. |
| BBT | change between baseline (Day 1) and after training (Day 3) | Box & Blocks Test (timed transfert of blocks from one space to the other, 3 trials/hand) |
| bi-Force on bimanual REACHING (REAplan robot) | change between baseline (Day 1) and after training (Day 3) | bimanual forces, forces exerted in the wrong direction by each arm (Newtons) |
| bi-CO on bimanual REACHING (REAplan robot) | change between baseline (Day 1) and after training (Day 3) | bimanual Coordination factor, mathematical measure of the phase coherence between speeds of both arms |
Countries
Belgium
Contacts
Primary ContactYves Vandermeeren, MD, PhD
Outcome results
None listed