Appetite
Conditions
Keywords
cereal-based products fortified with legumes, appetite regulation, postprandial glucose response, postprandial hormone responses
Brief summary
Legumes are rich source of proteins and dietary fibers which are associated with satiety and amelioration of postprandial glycemic response. The purpose of the study is to examine the effects of cereal-based products fortified with legumes on appetite regulation and body weight management.
Detailed description
Postprandial glycemic response as well as response of hormones related to appetite regulation after consumption of cereal-based products fortified with legumes will be evaluated. Apparently healthy subjects with normal body weight and overweight subjects will participate in the study (two protocols). Certain effects on metabolites related to the composition of the different products will be examined. The results of the study will help in the design of a long-term clinical trial regarding the effects of the functional products on body weight management in overweight subjects.
Interventions
OTHERCereal-legume product 1
The intervention examines the effect of cereal based product fortified with legumes-1 in appetite regulation in 1) subjects with normal body weight and 2) overweight subjects.
OTHERCereal-legume product 2
The intervention examines the effect of cereal based product fortified with legumes-2 in appetite regulation in 1) subjects with normal body weight and 2) overweight subjects.
OTHERCereal product
The intervention examines the effect of cereal product in appetite regulation in 1) subjects with normal body weight and 2) overweight subjects.
OTHERReference food
The intervention examines the effect of reference food in appetite regulation in 1) subjects with normal body weight and 2) overweight subjects.
Sponsors
National and Kapodistrian University of Athens
Harokopio University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Masking description
Foods do not differ in shape or color. Participants are blinded to the treatments.
Intervention model description
1. Healthy subjects with normal body weight receive different cereal-based products fortified with legumes or reference food in a randomized crossover design. Postprandial glycemic and hormonal responses are evaluated. 2. Overweight subjects receive different cereal-based products fortified with legumes or reference food in a randomized crossover design. Postprandial glycemic and hormonal responses are evaluated.
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* normal exercise and dietary habits * weight stable for at least 3 months before enrollment
Exclusion criteria
* pregnancy * diabetes * chronic medical illness * use of nutritional supplements * regular intense exercise * alcohol consumption \>2 drinks per day
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in glucose AUC | Time points: 0 (before food consumption), 30, 60, 90,120,180 minutes postprandially for each food (totally four times) | Change in glucose AUC after consumption of the products compared to the AUC after consumption of the reference food |
Countries
Greece
Outcome results
None listed