Acute Kidney Injury, Hypothermia
Conditions
Keywords
continuous renal replacement therapy
Brief summary
The present study aims at testing if the TherMax blood warmer is more accurate and reliable in reaching and maintaining chosen target temperature during continuous renal replacement therapy as compared to the Prismaflo IIS blood warmer used for the PrismaFlex system.
Detailed description
Blood warming devices during continuous renal replacement therapy (CRRT) have not been adequately tested. The novel TherMax blood warmer for the newly introduced PrisMax System heats blood and replacement solutions via a dry heat plate system. In contrast, the PRISMAFLO IIS Blood Warmer for PRISMAFLEX System uses an electric heating sleeve on a standard CRRT filter set. Data on adverse events (AE) during continuous renal replacement therapy (CRRT) has been studied and one of the most common AE was hypothermia, reported in 44% of all cases. The present study aims at testing if the TherMax blood warmer is more accurate and reliable in reaching and maintaining chosen target temperature during CRRT as compared to the blood warmer used for the PrismaFlex system.
Interventions
DEVICEThermax Blood Warmer
Patients will be their own controls: Prior to-, during-, and after Thermax blood warming.
Sponsors
Skane University Hospital
Karolinska University Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
The investigators will assess body temperature before-, during- and after Thermax blood warming treatment. Patients are essentially their own controls. Moreover, we will use historic data on the previous blood warmer for the Prismaflex device to assess temperature changes.
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Adult (18-100 years) critically ill patients treated with CRRT.
Exclusion criteria
* Patients under 18 years of age. Non-RRT patients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Temperature, accuracy | 24 hours | During use of Thermax; hourly difference between prescribed temperature-measured temperature; accuracy 0,1 Celsius |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Temperature, differences | 12-18 hours (six hour warming period) | Difference to 36.5 Celsius, std deviation, interquartile range: Prior to Thermax, during Thermax and after Thermax |
| Historic comparator | 24 hours | Using registry/PDMS data, how did the old blood warmer perform with regards to temperature |
Countries
Sweden
Outcome results
None listed