Lymphoma
Conditions
Brief summary
The diagnosis of lymphoma bone marrow infiltration is very important for the staging and treatment mode of lymphoma. Traditional bone marrow cytology and pathology examinations are only performed locally, and missed diagnosis is possible. The study explore the value of multi-parameter pelvic magnetic resonance in detecting bone marrow infiltration with newly diagnosed lymphoma patients . This study also explore the consistency of pelvic magnetic resonance and PET/CT for detection of lymphoma bone marrow infiltration.
Interventions
None listed
Sponsors
Guangxi Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
8 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Lymphoma subtypes were diagnosed on the basis of tissue samples obtained by biopsy or surgery according to the criteria outlined in the current World Health Organization (WHO) classification of hematologic and lymphoid malignancies, by are reference pathologist. * Patients who gave written informed consent were referred for MRI. * Stable physical medical conditions (patients conscious and comfortable, scheduled for an elective diagnostic imaging).
Exclusion criteria
• Pregnancy, general contraindications to MRI.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Agreement Between MRI and Bone marrow cytology, pathology and follow-up at Diagnosis | Within 30 days prior to start of chemotherapy | MRI-positive lesions that cannot be confirmed by bone marrow cytology and pathology will be confirmed by MRI follow-up. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Agreement Between MRI and 18F-FDG PET/CT at Diagnosis | Within 30 days prior to start of chemotherapy | Region based agreement (%; kappa value) of MRI with 18F-FDG PET/CT at diagnosis. |
Countries
China
Outcome results
None listed