Validation of a Novel Frailty Index in Surgical Cohorts

Testing and Validation of a Novel Frailty Index in a Surgical Cohort

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03971851

Enrollment

50000

Registered

2019-06-03

Start date

2005-01-01

Completion date

2020-04-01

Last updated

2020-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia Morbidity, Perioperative Complication, Surgery--Complications

Brief summary

This study will validate the utility of a novel frailty index that uses ICD diagnoses to call frailty severity in a surgical cohort of patients 65 and older

Interventions

OTHERFrailty risk groups

Patients older than 65 will be separated into groups of varying frailty risk

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients 65 years or older, undergoing any surgery at Landspitali University Hospital with an anesthesia team involved

Exclusion criteria

* No American Society of Anesthesiology classification provided

Design outcomes

Primary

Measure	Time frame	Description
30-day mortality	30-days	Mortality within 30 days of surgery in each of the three frailty risk groups
Time to hospital readmission	Up to 180 days	For patients surviving index hospitalization, the proportional hazard ratio of readmission between the three frailty group

Secondary

Measure	Time frame	Description
Long-term mortality	Up to 14 years	Long-term mortality of the three different frailty risk groups, compared with proportional hazard modeling
Prolonged hospital length-of stay	3 months	Incidence of patients staying more than 10-days after surgery in the three frailty risk cohorts

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026