Acute Ischaemic Stroke
Conditions
Keywords
Cerebrovascular disorders, Magnetic resonance imaging, Neuroimaging, Prognosis, Stroke
Brief summary
Magnetic resonance imaging (MRI) is the diagnostic cornerstone for precisely identifying acute ischaemic strokes and locating vascular occlusions. It was observed that a post-contrast three-dimensional turbo-spin-echo T1weighted sequence showed striking post-contrast vascular hyperintensities (PCVH) in ischaemic territories. The aim is to evaluate the prevalence and the meaning of this finding. This study included 130 consecutive patients admitted for acute ischaemic stroke with a 3-T MRI performed in the first 12 h of symptom onset from September 2014 through September 2016. Two neuroradiologists blinded to clinical data analysed the first MRI assessments.
Interventions
OTHERMRI images review
MR images were reviewed by one junior radiologist and one senior neuroradiologist, both blinded to clinical, therapeutic and follow-up data.
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged 18 and older at onset of an acute ischaemic stroke * Availability of at least one pre-therapeutic MRI performed in our centre within 12 h of stroke onset, including a post-contrast 3D TSE T1-weighted sequence.
Exclusion criteria
* Patients with posterior fossa strokes * Patients with known intracranial vasculitis or MoyaMoya disease * Presence of severe MR imaging artefacts preventing correct interpretation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| overal survival | 7 years | from the AR-PML diagnosis date to that of death or censored on 31 December 2015 |
Outcome results
None listed