Cesarean Section Complications, Cesarean Wound Disruption, Suture Related Complication, Wound Heal
Conditions
Keywords
cesarean section, scar heal, isthmocele, suture material, saline infusion sonography
Brief summary
We want to compare the effects of 2 suture materials (monofilament and multifilament) on healing of the uterine scar after a cesarean delivery.
Detailed description
Cesarean section (CS) is the most common type of obstetric surgery. When medically justified, CS can effectively prevent maternal and perinatal mortality and morbidity however, there are many short and long-term complications of CS. One of the most common complications is the CS scar defect. CS scar defects can develop after transverse incision of the lower uterine segment, which may result in prolonged postmenstrual bleeding, spotting, pelvic pain, and infertility. Suture material is an essential part of any major surgery, serving to hold opposing tissues together and accelerate the healing process, resulting in decreased scarring of the affected areas. We sought to evaluate the effects of different synthetic absorbable suture materials on cesarean scar defect formation.
Interventions
OTHERMonofilament suture
1.0 monofilament synthetic absorbable suture for closure of the low transverse uterine incision
OTHERMultifilament suture
1.0 multifilament synthetic absorbable suture for closure of the low transverse uterine incision
Sponsors
Bezmialem Vakif University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* singleton pregnancy at term \>37 weeks of gestational age
Exclusion criteria
* history of previous cesarean section * history of previous uterine surgery * multiple gestation, placenta previa, polyhydramnious, fetal macrosomia * uterine atony history * gestational diabetes mellitus, gestational hypertension, preeclampsia, current or previous history of heart disease, liver, renal disorders or known coagulopath * active labor (with regular uterine contractions and cervical dilatation \>4 cm
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The healing ratio | 6 months | Six months after the operation, the integrity of the cesarean scar at the uterine incision site will be assessed by hydrosonography. The healing ratio will be calculated as the thickness of the residual myometrium covering the defect, divided by the sum of the thickness of the residual myometrium covering the defect and the height of the wedge-shaped defect. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| blood loss | 24 hours | The hemoglobin and hematocrit values will be measured 24 hours after CS |
| additional sutures | 2 hours | number of additional hemostatic sutures |
Countries
Turkey (Türkiye)
Outcome results
None listed