Drusen
Conditions
Brief summary
To investigate the efficacy and safety of sub-threshold micro-pulse laser therapy for drusen of dry age-related macular degeneration (AMD) .
Interventions
DEVICElaser treatment
sub-threshold micro-pulse laser treatment
Sponsors
The Eye Hospital of Wenzhou Medical University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Older than 50 years of age. 2. Male or female patients with nonexudative AMD with a drusen diameter of at least 125um in the central 3mm circle 3. clear media to perform colour, red-free imaging and fundus fluorescein angiography, fundus autofluorescence imaging and OCT. 4. Able to give an informed consent.
Exclusion criteria
1. Presence of other macular disease such as epiretinal membrane, macular telangiectasia. 2. unclear media that no clear colour, red-free imaging and fundus fluorescein angiography, fundus autofluorescence imaging and OCT can performed. 3. Ocular or periocular infections.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in macular drusen volume | 6 and 12 months | Mean change in macular drusen volume on optical coherence tomograph(OCT) |
| Change in macular drusen area | 6 and 12 months | Mean change in macular drusen area on OCT |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in visual acuity | 6 and 12 months | Mean change in best-corrected visual acuity |
Countries
China
Contacts
Primary ContactYing Huang
Outcome results
None listed