Ewing Sarcoma of Bone
Conditions
Brief summary
This is single institution cases series review of histological and clinical data
Detailed description
Investigators will retrieve from the database of the Rizzoli institute all the cases with a histological diagnosis of Ewing sarcoma from 01 Jan 1982 to 31 Dic 2012
Interventions
BEHAVIORALScoring tool in Chemotherapy-induced necrosis in Ewing sarcoma
The aim of the present study is to evaluate which is the best scoring tool to determine the histological response to chemotherapy in localized Ewing sarcoma of bone. The study will exam all the different systems to evaluate the histological necrosis after neo-adjuvant chemotherapy in all patients with localized Ewing sarcomas of bone surgically treated between 1982 and 2012.
Sponsors
Istituto Ortopedico Rizzoli
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. Male and female patients surgically treated at Rizzoli Institute from 01 Jan 1982 to 31 Dic 2012 2. Patients with diagnosis of Ewing sarcoma of bone who have had neo-adjuvant chemotherapy 3. Diagnosis of Ewing sarcoma localized
Exclusion criteria
1. Metastatic disease at presentation 2. Soft tissue origin 3. Radiotherapy before surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| retrospective analysis of cases of Ewing sarcomas | at baseline (Day0) | Investigators will exam the histological response to chemotherapy in localized Ewing sarcoma of bone and correlate it to clinical outcome. |
Countries
Italy
Outcome results
None listed