Meningitis
Conditions
Brief summary
Klebsiella pneumoniae is implicated in the occurrence of severe pneumonia. Most Klebsiella pneumoniae infections are associated with care and occur in patients with compromised immune defenses. More recently, cases of hepatic abscess and acute community meningitis related to strains of Klebsiella pneumoniae have been reported. The mortality of these infections is important, most often due to a delayed diagnosis. The poor prognostic factors reported in the literature for very low numbers are: advanced age, coma, septic shock, glyceryachia \<10mg / dL and proteinuria\> 750 mg / dL. In addition, no study has specifically focused on the factors of occurrence and factors associated with Klebsiella sp. Indeed, meningitis related to Klebsiella pneumoniae seems to be a rare but probably underestimated event whose risk factors, clinical presentation, microbiological are little known and the treatment modalities of this severe infection are not codified.
Interventions
None listed
Sponsors
Fondation Hôpital Saint-Joseph
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Man or Woman whose age ≥ 18 years * Patient with meningitis Klebsiella sp., hospitalized in one of the hospitals of the Clinical Microbiology Group * Francophone patient
Exclusion criteria
* Patient under tutorship or curatorship * Patient deprived of liberty * Patient under safeguard of justice * Patient opposing his participation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Characterize meningitis with Klebsiella pneumoniae | Day 1 | This corresponds to characterize Klebsiella pneumoniae meningitis, portal entry, secondary infection, associated antibiotic and associated therapies and the clinical course of patients. |
Countries
France
Outcome results
None listed