Chronic Heart Disease, Chronic Heart Failure, Heart Failure
Conditions
Keywords
HFmrEF, HFrEF, HFpEF, Heart Failure
Brief summary
This study characterizes heart failure patients who attended the University Hospital Würzburg. The primary aim is a better understanding of the relationships and differences between the subgroups HFrEF (EF \< 40%), HFmrEF (EF 40-49%), and HFpEF (EF\>50%), contributing to an improved diagnosis, prognosis and therapy of patients with heart failure.
Detailed description
The varying clinical picture of heart failure (HF) represents a major challenge for patient care in Germany. HF is one of the most common reasons for hospitalization in the Western world. In the chronic course of heart failure, affected patients are committed to morbidity, lifelong therapy and high risk of cardiac decompensation, also associated with high mortality. Heart failure patients, who visited the Cardiology Department of the University Hospital Wuerzburg, shall be analyzed with regard to all clinical data and outcome. This retrospective work should help to better understand the three groups HFrEF (EF \< 40%), HFmrEF (EF 40-49%) and HFpEF (EF\>50%) and help identifying similarities and differences between the groups. Hereby we hope for progress in diagnostic, prognostic and therapeutic aspects of heart failure.
Interventions
OTHERTime (outcome)
Sponsors
Wuerzburg University Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis: Heart failure * Minimum of two echocardiographic examinations in a minimum time frame of six months * Patients must have reached the age of 18
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Long-term survival in heart failure patients with preserved, mid-range or reduced left ventricular ejection fraction | 1 year follow up after last examination | Survival of patients with heart failure extracted from medical record or by telephone interview |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Impact of clinical imaging and laboratory parameters on long-term survival in heart failure patients with precerved, mid-range or reduced left ventricular ejection fraction | 6 months | Parameters are derived from standard echocardiography, cardiac magnetic resonance imaging and blood testing. |
Countries
Germany
Contacts
Primary ContactPeter Nordbeck, MD, PhD
Backup ContactKai Hu, MD
Outcome results
None listed