Tabagism
Conditions
Keywords
OCT-A, smokers, vapers, non-smokers/non-vapers, nicotine, retinal micro-vascularization
Brief summary
The main hypothesis is the nicotine is associated with a modification of retinal micro-vascularization. Patients will be recruited during their ophthalmologic consultation at the Rothschild Foundation, an OCT-A will be realized and data relating to medical history, oral contraceptive intake and nicotine consumption via cigarette or e-cigarette data will be collected. The objective is to seek an association between retinal vascular density and inhaled nicotine intake.
Interventions
DIAGNOSTIC_TESTOCT-A (Optical Coherence Tomography)
Included patients will have an OCT-A and will be questioned about their nicotine intake, their background and taking an oral conception
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* For group of smokers: Patient reporting active smoking for at least 3 months and at least 1 cigarette per day on average over a week * For group of vapers : Patient using exclusively the electronic cigarette with a nicotine level of more than 6mg/ml for at least 3 months and at least 1 times per day on average over a week. * For group of no-smokers no-vapersNon-smoking and no vaping, for more than 6 months Non-inclusion criteria: * Caffeine intake within 2 hours prior to the OCT-A exam * ametropia greater than + 3 dioptres of hyperopia or-3 dioptres of myopia * astigmatism greater than 2 dioptres * Known retinal or retina vascular pathology
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Density of retinal vascular Plexus (quantitative variable expressed as a percentage) using OCT-A. | At the inclusion consultation |
Countries
France
Outcome results
None listed