Cerebrovascular Accidents, Stroke
Conditions
Keywords
optical coherence tomography (OCT-A), color fundus photography (CFP), Retinal microvascularization, Cerebral microangiopathy
Brief summary
The hypothesis is that in patients with stroke, abnormalities of retinal microvascularization shown on color fundus photography and the depletion of retinal capillary density evaluated by OCT-A are markers of acute impairment of microcirculation of the central nervous system and are correlated with lesions on brain imaging. Patients hospitalized for stroke MRI-confirmed, will be included. An ophthalmologic assessment including color fundus photography (CFP) and OCT-A will be carried out after stabilization and at 3 months follow-up. Outcomes assessor will be blinded.
Interventions
DIAGNOSTIC_TESTcolor fundus photography (CFP) and OCT-A
Included patients will have an ophthalmologic assessment (OCT-A and CPF) after stabilization and at 3 months follow-up.
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Acute ischemic stroke * With cerebral microangiopathy (defined by a SVD score \> 1)
Exclusion criteria
* Acute hemorrhagic stroke * Anophthalmia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of an anomaly in color fundus photography or an anomaly of retinal capillary density to OCT-A | 3 months |
Countries
France
Outcome results
None listed