Serum Ferritin and Hepicidin Concentration in Chronic Periodontitis Patients With T2DM

Decreased Ferritin And Increased Hepcidin Serum Levels In Periodontitis Patients With Diabetes Mellitus Type 2. Controlled Before-And-After Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03964428

Enrollment

Registered

2019-05-28

Start date

2018-09-01

Completion date

2019-01-30

Last updated

2019-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis, Type2 Diabetes

Keywords

periodontitis, ferritin, hepicidin, type 2 diabetes mellitus, non surgical perioontal therapy

Brief summary

serum level of ferritin and hepicidin were evaluated in periodontitis patient with and without type 2 diabetes before and after non surgical periodontal treatment to clarify their in periodontal disease

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

30 Years to 50 Years

Inclusion criteria

* patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm with T2DM * systemically healthy patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm * healthy subjects had clinically healthy gingiva with ≤ 3mm pocket probing depth (PPD), nearly zero plaque index (PI), gingival index (GI), zero CAL.

Exclusion criteria

* (I) Pregnancy or lactation, (II) History of receiving professional periodontal treatment during the past 6 months; (III) Treatment with any type of medications and/ or antibiotics during the past 3 months and (IV) Current or former smokers.

Design outcomes

Primary

Measure	Time frame	Description
ferritin concentration	0-3 months	ng/ml
hepicidin concentration	0-3 months	ng/ml

Countries

Egypt

Outcome results