Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP

Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP: A Randomized Controlled Clinical Trial.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03963791

Acronym

REEPP-WSC

Enrollment

Registered

2019-05-28

Start date

2019-10-05

Completion date

2020-06-01

Last updated

2019-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries

Brief summary

This research is conducted to compare the remineralization efficacy of eggshell powder gel and CPP-ACP (MI paste) on post-orthodontic white spot lesions.

Interventions

OTHEREggshell powder gel

Eggshell powder gel produced from chicken eggs.

OTHERCPP-ACP crème

A water-based, sugar-free topical cream containing Recaladent (CCP-ACP) which is derived from the milk protein.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

13 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* A patient who has just completed a comprehensive orthodontic treatment. * Presence of at least one WSL, DIAGNOdent score (0-20). * Age range between 13 and 35years.

Exclusion criteria

* Patients are unable to return for recall appointments. * High caries risk. * Have plaque accumulation and a periodontal problem * In progress treatment of chronic disease. * Presence of abnormal oral, medical, or mental condition (including any milk-related allergies or any medical condition involving kidneys or salivary glands). * Presence of dentin caries, enamel hypoplasia or restorations on maxillary anterior teeth.

Design outcomes

Primary

Measure	Time frame	Description
white spot lesion progression.	6 months.	The change in the lesion fluorescence will be evaluated using diode laser fluorescence device (Diagnodent).

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026