Cartilage Injury, Knee Osteoarthritis
Conditions
Keywords
Extracorporeal Shock Wave Therapy, Knee Osteoarthritis, Cartilage Injury
Brief summary
In this study, the effectiveness of ESWT in the treatment of knee OA was investigated from the perspective of cartilage injury，and to prove that shockwave could delay the early and middle stage OA progression by improving cartilage condition
Interventions
DEVICEshock wave device
The experimental group (group ESWT) guided by ultrasound: conventional rehabilitation training is given priority to with strength training, application of pain when necessary, under the guidance of ultrasound ESWT treatment control group (routine rehabilitation group) : conventional rehabilitation training is given priority to with strength training, oral pain when necessary, under the guidance of ultrasound ESWT treatment (shock energy flow density of 0)
Sponsors
Peking University Third Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Knee joint ROM normal or near normal: flexion 110 ° or reach 0 ° or less * MR prompt exist cartilage damage, there is no lack of full-thickness cartilage * Kellgren - Lawrence (K - L) grade II - III grade * The international association of cartilage repair cartilage damage grading system (ICRS) class I - III * Informed consent and sign relevant documents * Follow doctor's instructions and follow up on time
Exclusion criteria
* Metabolic arthritis * Trauma of bone joint * Inflammatory diseases * Previous knee surgery history * History of knee cavity injection in the past 6 months * Serious cardiovascular diseases, pulmonary diseases or other serious diseases affecting survival, etc
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| magnetic resonance imaging of knee | Baseline (before treatment) | t2 mapping |
Countries
China
Contacts
Primary Contactmouwang 谋望 zhou, master
Backup Contactmingzhen 明真 Lee, bachelor
Outcome results
None listed