Anxiolytics
Conditions
Brief summary
In this study, the therapeutic drug monitoring of anxiolytics is carried out among children to obtain the drug concentration, clinical efficacy and safety data of children patients in different gender and age groups. Then the investigators analyze the relationship between blood drug concentration and efficacy and safety, and provide recommendations for the treatment window of anxiolytics in Chinese children.
Interventions
DRUGMidazolam/diazepam/propofol
Therapeutic drug monitoring of anxiolytics
Sponsors
Wei Zhao
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
29 Days to 18 Years
Healthy volunteers
No
Inclusion criteria
* Anxiolytics was used for therapeutic purposes; * Age:≤18 years; * Patients with therapeutic concentration monitoring of anxiolytics.
Exclusion criteria
* Patients without therapeutic concentration monitoring of anxiolytics; * The blood concentrations of the patient was not approved by the quality control center * Use foods or products that inhibit or induce CYP 3A activity.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Plasma drug concentration | Through study completion, an average of 14 days | To detect the plasma concentrations of teicoplanin at therapeutic drug monitoring (TDM). |
Countries
China
Contacts
Primary ContactZhao Wei, Ph.D
Outcome results
None listed